| Physical effects: Vasoconstriction |
From PsychonautWiki
Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels (in particular the large arteries and small arterioles). The process is the opposite of vasodilation, the widening of blood vessels.
This effect can be described as the sensation of feelings of tightness within one's arms and legs. It occurs under the influence of certain substances and can range from mild in its effects to extremely uncomfortable.