Substituted morphinan |
 |
This article is a stub. As such, it likely contains incomplete or wrong information. You can help by expanding it. |
Morphinans are a class of chemicals that include compounds with psychoactive effects.
Contents
Chemistry
Morphinans are made up of the morphinan molecule with altering functional groups attached on the numbered carbons. Morphinan is comprised of a phenanthrine core of three fused benzene rings, two of which are saturated. A fourth six-membered nitrogen-containing ring is attached to the core at carbons 9 and 13.
Pharmacology
The morphinans are a large chemical class and compounds within it have differing pharmacological effects. Active morphinan derivatives often act upon the NMDA receptor, the μ-opioid receptor and the σ1 and σ2 sigma receptors.
Examples
Morphinans are seen throughout organic chemistry including many analgesic, antitussive and anaesthetic compounds.
Dissociative drugs
Analgesic drugs
See also
References
 |
This article does not cite any references. You can help by adding some. |
