Bromantane

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Bromantane
Skeletal structure of bromantane
Chemical Nomenclature
Common names	Bromantane, bromantan
Substitutive name	Ladasten
Systematic name	N-(4-bromophenyl)adamantan-2-amine
Routes of Administration
Oral Dosage NOTE: Bromantane is absorbed more quickly in females than in males. Thus, females will experience a shorter duration of effects. Bearing this in mind, always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. Threshold < 10 mg Light 10 - 50 mg Common 50 - 100 mg Strong 100 - 200 mg Heavy > 200 mg Duration Total 6 - 10 hours Onset 30 - 60 minutes Peak 2 - 4 hours

Bromantane (trade name Ladasten / Ладастен) is a Russian pharmaceutical drug developed in the late 1980s that possesses both stimulant and anxiolytic properties. Although it is a commonly used medication in Russia and surrounding countries, it has not gained widespread recognition or pharmaceutical use in other countries. During the 1996 Olympic Games in Atlanta, 5 different Russian athletes tested positive for bromantane use.

A study conducted on human subjects displayed bromantane's ability to improve endurance and work capacity during stressful and intense conditions. This is because bromantane works as an actoprotector, a substance that makes the body more stable under physical duress without increasing oxygen consumption.

Chemistry

This chemistry section is incomplete. You can help by adding to it.

Adamantane molecule

Bromantane is a chemical derivative of adamantane, a polyhedral organic compound. Although hundreds of substances have been derived from adamantane, bromantane remains the most well-studied. Bromantane's structure consists of adamantane fused with a 4-bromoaniline molecule.

Pharmacology

Bromantane is atypical among stimulants in the sense that it inhibits serotonin reuptake in addition to inhibiting dopamine reuptake. It also increases levels of norepinephrine, but its means of doing so are unclear. Bromantane's anxiolytic properties are due to its strengthening of GABA-ergic mediation.

Subjective effects

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects.

Physical effects

• Stamina enhancement
• Stimulation
• Dehydration
• Vasoconstriction
• Increased blood pressure
• Muscle relaxation

Cognitive effects

• Anxiety suppression
• Stamina enhancement
• Focus enhancement
• Thought acceleration
• Analysis enhancement
• Wakefulness
• Memory enhancement
• Motivation enhancement
• Cognitive euphoria

Toxicity and harm potential

Lethal dosage

The LD₅₀ of bromantane in mice has been established at 8100 mg/kg.

It is strongly recommended that one use harm reduction practices when using this drug.

Legal issues

• Russia - Bromantane is a prescription drug in Russia, its country of origin.
• United States - Bromantane is uncontrolled in the United States, and has not been approved by the FDA for human use. However, this has led nootropic vendor websites to sell bromantane under the label of "not for human consumption."

See also

• Responsible use
• Tianeptine
• Noopept
• Nootropics