AL-LAD
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AL-LAD
Molecular structure of AL-LAD
AL-LAD.png
Chemical Nomenclature
Common names AL-LAD, Aladdin
Substitutive name 6-allyl-6-nor-lysergic acid diethylamide
Systematic name (6aR,9R)-N,N-diethyl-7-(prop-2-en-1-yl)-4,6,6a,7,8,9-hexahydroindolo-[4,3-fg]quinoline-9-carboxamide
Class Membership
Psychoactive class Psychedelic
Chemical class Lysergamide
Routes of Administration



Oral
Dosage
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.
DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation.
This dosage and duration information has been sourced from TripSit
Threshold 10 - 40 µg
Light 40 - 75 µg
Common 75 - 175 µg
Strong 175 - 250 µg
Heavy 250 µg +
Duration
Total 6 - 10 hours
Onset 45 - 120 minutes
Peak 3 - 5 hours
Offset 3 - 4 hours
After effects 2 - 5 hours









Summary sheet: AL-LAD

6-allyl-6-nor-lysergic acid diethylamide (abbreviated AL-LAD, also known as Aladdin) is a semi-synthetic hallucinogenic psychedelic drug of the lysergamide family, as described by Alexander Shulgin in the book TiHKAL (Tryptamines i Have Known And Loved).

This substance has little to no history of human usage. However, it has recently become commonly marketed along side of LSZ as a legal alternative to LSD through online research chemical vendors.

Chemistry

AL-LAD, or 6-allyl-6-nor-lysergic acid diethylamide, is a semi-synthethic alkaloid of the lysergamide famiy. AL-LAD is a structural analogue of lysergic acid, with an N,N-diethylamide functional group bound to RN of the chemical structure. This core polycyclic structure is an indole derivative, and has tryptamine and phenethylamine groups embedded within it.

AL-LAD's structure contains a bicyclic hexahydroindole fused to a bicyclic quinoline group (nor-lysergic acid). AL-LAD does not contain a methyl group substituted at R6 of its nor-lysgeric acid skeleton, this is represented by the nor- prefix. Instead, AL-LAD is substituted at R6 with an allyl group containing a methyelene bridge bound to a vinyl substituent. At carbon 8 of the quinoline a N,N-diethyl carboxamide is bound.

AL-LAD is a chiral compound with two stereocenters at R5 and R8. AL-LAD, also called (+)-D-AL-LAD, has an absolute configuration of (5R, 8R). The three other stereoisomers of AL-LAD do not have psychoactive properties.[1]

Pharmacology

Main article: Serotonergic psychedelic

This compound likely acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from AL-LAD's efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

AL-LAD shares many common traits with LSD; it appears to be equal in potency as well as similar in mechanism although the progression and duration of effects are compressed due to its metabolic differences.

Subjective effects

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects.

While the subjective effects are almost identical to that of LSD, AL-LAD is significantly shorter in its duration. In comparison to its structural relative LSZ, it is reported to be more introspective and stoning.

Physical effects

  • Spontaneous tactile sensations - The "body high" of AL-LAD can be described as proportionally intense in comparison to its accompanying visual and cognitive effects. It behaves as a euphoric,AL-LAD is usually considered to be very energetic and stimulating without being forced. For example,an intense sensation of suddenly becoming aware of and being able to feel every single nerve ending across a person's entire body all at once is consistently present.
  • Bodily control enhancement
  • Increased heart rate
  • Pupil dilation,but for most it maintains a steady presence that rises with the onset and hits its limit once the peak has been reached. At moderate to high doses of AL-LAD,climbing or dancing. In comparison,fast-moving,other more commonly used psychedelics such as psilocin are generally sedating and relaxing.
  • Nausea - Mild nausea is occasionally reported when consumed in moderate to high dosages and either passes instantly once the tripper has vomited or gradually fades by itself as the peak sets in.
  • Tactile enhancement - Feelings of enhanced tactile sensation are consistently present at moderate levels throughout most AL-LAD trips. Once 8A Geometry is reached,sharp and location specific tingling sensation. For some it is manifested spontaneously at different unpredictable points throughout the trip,this sensation will usually hit its highest level and become so overwhelming that people find themselves writhing on the floor in complete pleasure.
  • Stimulation - In terms of its effects on the physical energy levels of the tripper,walking,when taken in any environment it will usually encourage physical activities such as running.

Cognitive effects

The cognitive effects of AL-LAD can be broken down into several components which progressively intensify proportional to dosage. In comparison to other psychedelics such as Psilocin, LSA and ayahuasca, AL-LAD is significantly more stimulating and fast-paced in terms of the specific style of thought stream which it produces and contains a large number of potential effects.

The most prominent of these cognitive effects generally include:

Visual effects

Enhancements

Distortions

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of 2C-B or 2C-I than Psilocin, LSA or DMT. It can be comprehensively described through its variations as primarily intricate in complexity, algorithmic in form, unstructured in organization, brightly lit, colourful in scheme, organic in feel, multicoloured in scheme, flat in shading, soft in its edges, large in size, slow in speed, smooth in motion, either angular or round in its corners, non-immersive in depth and consistent in intensity. At higher dosages, it consistently results in states of Level 8A visual geometry over Level 8B.

Hallucinatory states

AL-LAD is capable of producing a full range of low and high level hallucinatory states in a fashion that is significantly less consistent and reproducible than that of many other commonly used psychedelics. These effects include:

Auditory effects

Toxicity and harm potential

Lolol.pngMain articles: Research chemicals § Toxicity and harm potential & Responsible use § Hallucinogens

The toxicity and long-term health effects of recreational AL-LAD use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because AL-LAD is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried AL-LAD suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption. It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance and addiction potential

AL-LAD is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of AL-LAD are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). AL-LAD presents cross-tolerance with all psychedelics, meaning that after the consumption of AL-LAD all psychedelics will have a reduced effect.

Legal issues

It is unclear in many countries whether this compound is legal or not and one should take precaution by assuming it is illegal to avoid legal issues.

  • USA - AL-LAD is illegal in the U.S. under the analogue act.
  • UK - The U.K. ban, recommended by the ACMD on June 10th, 2014, came into effect on January 7th, 2015. AL-LAD was specifically named in the U.K. Misuse of Drugs Act as a Class A drug, despite admission from the ACMD that they were unable to identify any harm associated with its use.[2]
  • Switzerland - 21 additional chemicals were added to the list of illegal substances including AL-LAD in December 2015.[3]
  • Latvia - AL-LAD is illegal in Latvia. Although it isn't officially scheduled, it is controlled as an LSD structural analog due to an amendment made on June 1th, 2015.[4]
  • Sweden - Following its sale as a designer drug, AL-LAD was made illegal in Sweden on 26 January 2016.[5]

Experience reports

Anecdotal reports which describe this compound within our experience index include:

Additional experience reports can be found here:

See also

External links

References

  1. ↑ http://isomerdesign.com/PiHKAL/read.php?domain=tk
  2. ↑ ACMD (10 June 2014). "Update of the Generic Definition for Tryptamines". UK Home Office. p. 12. Retrieved 10 June 2014. 
  3. ↑ https://www.admin.ch/opc/de/official-compilation/2015/5093.pdf
  4. ↑ Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (2.4.punkts) | http://likumi.lv/doc.php?id=121086
  5. ↑ (in Swedish) Folkhälsomyndigheten. | https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2016/januari/31-nya-substanser-klassas-som-narkotika-eller-halsofarlig-vara/
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