2C-T-7

2C-T-7 can be fatal when insufflated or combined with some drugs. It is strongly discouraged to insufflate (snort) 2C-T-7 or combine it with these other substances. Please see this section for more details.

2C-T-7
The skeletal formula of 2C-T-7.
Chemical Nomenclature
Common names	2C-T-7
Substitutive name	2,5-Dimethoxy-4-n-propylthiophenethylamine
Systematic name	2-[2,5-Dimethoxy-4-(propylthio)phenyl]ethanamine
Class Membership
Psychoactive class	Psychedelic
Chemical class	Phenethylamine
Routes of Administration
Oral Dosage WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy. Threshold 3 - 5 mg Light 10 - 20 mg Common 15 - 30 mg Strong 10 - 50 mg Heavy 50 mg + Duration Total 5 - 10 hours Onset 60 - 90 minutes Come up 5 - 30 minutes Peak 3 - 7 hours Offset 1 - 2 hours After effects 2 - 4 hours Insufflated Dosage WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy. Threshold 1 - 3 mg Light 2 - 10 mg Common 5 - 15 mg Strong 5 - 15 mg Heavy 15 - 25 mg 2C-T-7 has been fatal when insufflated at heavy doses of 30mg or higher. Duration Total 3 - 7 hours Onset 5 - 15 minutes Come up 20 - 60 minutes Peak 2 - 4 hours Offset 1 - 2 hours After effects 1 - 2 hours

Summary sheet: 2C-T-7

2C-T-7 (2,5-dimethoxy-4-propylthiophenethylamine) is a psychedelic phenethylamine of the 2C-x family. It was first synthesized by Alexander Shulgin in his book PiHKAL: A Chemical Love Story. This particular substance is part of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important phenethylamine compounds, all of which except mescaline he developed and synthesized himself. They are found within the first book of PIHKAL, and are as follows: Mescaline, DOM, 2C-B, 2C-E, 2C-T-2 and 2C-T-7.

2C-T-7 is a highly dose sensitive psychedelic known for its strong visuals and intense body load. Many reports also indicate that the effects of this chemical may be overly intense for those who are not already experienced with psychedelics.

Chemistry

General formula of phenethylamine molecule.

2C-T-7 or 2,5-dimethoxy-4-propylthiophenethylamine is a substituted phenethylamine featuring a phenyl ring bound to an amino (NH₂) group through an ethyl chain. 2C-T-7 belongs to the 2C family of phenethylamines, which contain methoxy functional groups CH₃O- attached to carbons R₂ and R₅ of the benzene ring. 2C-T-7 is also substituted at R₄ with a propyl thioether group. 2C-T-7 is analogous to 2C-T-2; the two differ by the length of the alkane chain in their thioether functional group.

Pharmacology

Main article: Serotonergic psychedelic

2C-T-7's psychedelic effects have been shown to come from its efficacy at the 5-HT_2A receptor as a partial agonist. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

As the 2,5-desmethoxy derivative of 2C-T-7 has been shown to be a moderate monoamine oxidase A inhibitor, this substance may likewise have MAOI effects.

Subjective effects

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects.

Physical effects

• Spontaneous tactile sensations - The "body high" of 2C-T-7 is intense but, in comparison to 2C-E or 2C-B, it can be considered mild though is still capable of becoming very powerful and highly physically euphoric. It is similar yet distinct from the "body high" experienced on 2C-E, 2C-B, and LSD. The sensation itself can be described as intense and will manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.
• Stimulation - In terms of its effects on the physical energy levels of the tripper 2C-T-7 is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of other phenethylamines such as 2C-B, 2C-E and 2C-P.
• Bodily control enhancement - Although this component is capable of manifesting itself in a distinct and noticeable fashion for most users it does not generally seem to be as apparent or intense as the same component found within LSD and 2C-B.
• Tactile enhancement
• Nausea - Mild to extreme nausea is commonly reported when consumed in moderate to high dosages and either passes once the tripper has vomited or gradually fades by itself as the peak sets in.
• Temperature regulation suppression
• Increased heart rate
• Increased blood pressure
• Pupil dilation
• Headaches

Cognitive effects

The head space of 2C-T-7 is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high dosages.

The total sum of these cognitive components regardless of the setting generally includes:

• Emotion enhancement
• Thought acceleration
• Novelty enhancement
• Time distortion
• Increased music appreciation
• Analysis enhancement
• Personal bias suppression
• Conceptual thinking
• Memory suppression
• Ego death
• Immersion enhancement
• Thought loops
• Feelings of interdependent opposites
• Delusions
• Unity and interconnectedness
• Wakefulness

Visual effects

Enhancements

• Visual acuity enhancement
• Colour enhancement
• Pattern recognition enhancement

Distortions

• Drifting (melting, flowing, breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, slow and smooth in motion, static in appearance and extremely realistic in style but with a subtle digital/cartoonish form.
• Tracers
• After images
• Symmetrical texture repetition
• Colour shifting
• Scenery slicing

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of 4-AcO-DMT or ayahuasca than that of LSD, 2C-B or 2C-I. They can be comprehensively described as structured in their organization, organic in geometric style, intricate in complexity, large in size, fast and smooth in motion, colourful in scheme, glossy in colour, sharp in their edges and equally rounded and angular in their corners. It gives off a contradictory natural and synthetic feel with slightly more mystical and shamanic undertones in comparison to other phenethylamines. At higher dosages they are equally likely to result in states of Level 8A visual geometry or Level 8B. There seems to be visual geometry that is extremely similar to 2C-E and 2C-P and can be described as equal in intensity or complexity and equal in proportion to the accompanying cognitive and physical effects.

Hallucinatory states

2C-T-7 produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. This holds particularly true in comparison to other substances within the phenethylamine family. These effects include:

• Transformations
• Internal hallucinations (autonomous entities; settings, sceneries, and landscapes; alterations in perspective and scenarios and plots) - This effect is very consistent in dark environments at appropriately high dosages. They can be comprehensively described through their variations as lucid in believability, interactive in style, new experiences in content, autonomous in controllability, geometry-based in style and almost exclusively of a personal, religious, spiritual, science-fiction, fantasy, surreal, nonsensical or transcendental nature in their overall theme.

Auditory effects

• Enhancements
• Distortions
• Hallucinations

Toxicity and harm potential

Main articles: Research chemicals § Toxicity and harm potential & Responsible use § Hallucinogens

There have been at least three reported deaths related to 2C-T-7 use as of August 2007, mainly at insufflated doses of 30 mg or more or combined with stimulants such as MDMA, as well as a number of very uncomfortably intense effects and hospitalizations due to the insufflation of 2C-T-7.

It is strongly discouraged to snort 2C-T-7 because this can cause vomiting, numerous negative side effects, or death at high doses. In Erowid's Fall 2000 2C-T-7 survey, it was reported that the insufflation of 2C-T-7 resulted in more negative side effects than oral administration. It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance and addiction potential

2C-T-7 is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of 2C-T-7 are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 2C-T-7 presents cross-tolerance with all psychedelics, meaning that after the consumption of 2C-T-7 all psychedelics will have a reduced effect.

Dangerous interactions

If 2C-T-7 does have MAOI effects, this could indicate that 2C-T-7 is more likely to induce serotonin syndrome or general neurotransmitter overload (especially at high dosages) than other serotonergic psychedelics. This may make it dangerous to combine it with other MAOIs, stimulants and certain substances which releases neurotransmitters such as serotonin or dopamine. These substances include but are not limited to:

5-MeO-MiPT 2-C-T-7 AMT Ayahuasca Harmala alkaloids 2-AI 2-FMA 3-FPM 4-FA A-PVP Amphetamine Cocaine Ethylphenidate

Dehydroxyfluorafinil Isopropylphenidate MDAI MDMA Mephedrone Methamphetamine Methiopropamine Methylone Methylphenidate Modafinil Nicotine NM-2-AI Noopept

Legal issues

• United Kingdom - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.
• U.S. - On September 20, 2002, 2C-T-7 was classified as a Schedule I substance in the United States by an emergency ruling by the DEA. On March 18, 2004, the DEA published a final rule in the Federal Register which permanently placed 2C-T-7 in Schedule I.
• Latvia - 2C-T-7 is a Schedule I controlled substance in Latvia.
• Germany - 2C-T-7 is scheduled in Germany.
• Australia - In Australia, 2C-T-2 and 2C-T-7 are covered by the country's analogue drug laws.
• Canada - 2C-T-7 is unscheduled in Canada.
• Netherlands - The Netherlands was the first country in the world to ban 2C-T-7 after being sold in smartshops for a short period. After 2C-T-2 was first banned, 2C-T-7 quickly appeared on the market but was soon banned as well. 2C-T-7 is a list I drug of the Opium Law.
• Sweden - The drug is Schedule I in Sweden. 2C-T-7 was first classified as a health hazard under the act "Lagen om förbud mot vissa hälsofarliga varor" (translated as "the Act on the Prohibition of Certain Goods Dangerous to Health") that made it illegal to sell or possess as of April 1, 1999.

See also

• Responsible use
• 2C-T-2
• 2C-E
• 2C-B

External links

• 2C-T-7 (Wikipedia)
• 2C-T-7 (Erowid)
• 2C-T-7 experiences (Erowid)
• 2C-T-7 (PiHKAL)
• 2C-T-7 (TripSit)
• 2C-T-7 (Bluelight)